Finally got my Medeco cracked this weekend. Since I've been able to pick it many times with all 6 pins. The real secret for me was using the deep hook pictured. This worked better than my gem style pick I had been previously trying. My lock has a very low cut pin, so the deep hook helps a lot. It does occasionally have less precision getting between fore and aft pins that are sandwiched together when trying to distinguish, but that's less of a problem for me than over-setting was before.
Thanks to tumbl3r and this forum for the guidance. In the end I got a lot of confidence by just sticking it out and knowing others have done it.
CCW is getting pretty easy, but CW pick still eludes me. My lock doesn't go into a false set once picked to sheer CW, so rotating pins after that is much harder than doing the rotation CCW up front then picking to sheer. I've also experimented with CCW tension to align the rotation. Then switch to CW tension to pick to sheer. This works sometimes, but occasionally a pin slips out of rotation, probably just due to luck and how loose it is in binding order and if it gets bumped or not.